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A user-friendly, frequently updated reference guide that aligns with international guidelines and protocols.
Antivirals
Name | Dose (Adults) | Dose (Paediatric) | Precautions |
| Aciclovir | Prophylaxis: 400mg- BD Treatment: 800mg- 5 times a day- 14 days IV- HSV- 500mg- TDS | Prophylaxis->2yrs- 200mg-BD Treatment: 20mg/kg- 5times a day Inj. 10mg/kg-TDS- IV | Renal correction, avoid with amphotericin B, CSA, Monitor RFT Good hydration to avoid crystal nephropathy Avoid rapid infusion- Give over 2hrs IV- Watch for neurotoxicity |
| Valaciclovir | Prophylaxis- Routine- 500mg- BD For HSCT pts(CMV prophylaxis)- 2gm, PO- QID | ||
| Ganciclovir | 5mg/kg- BD- IV for 14-21 days then OD Slow over 1 hr Prophylaxis- IV- 5mg/kg- 5 days a week from engraftment till 100 days of transplant | 5mg/kg- BD | Renal correction, watch for cytopenia, CNS side effects, neuropathy, Hold if ANC <500, PL <25k, Adequate hydration W/F Retinal detachment (Ophthalmoscopy 6 weekly) Avoid with imipenem/cilastatin Use contraception during and after 90days after treatment |
| Valganciclovir | Prophylaxis: 900mg- OD-PO Therapy: 900mg- BD-PO | May cause BM suppression | |
| Entecavir | 0.5mg-OD-PO | ||
| Oseltamivir | Prophylaxis: 75mg-OD-PO Treatment: 75mg-BD-PO | May cause nausea |
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